Arthritis / Joint Pain Remedies 0

Cissus Quandrangularis (Veld Grape) for Joint Pain; Fact or Fiction?

Also known as “veld grape”, Cissus Quandrangularis a plant native to India.

It’s been used in traditional Ayurvedic medicine for centuries and is well known to have antioxidant, analgesic, and anti-inflammatory properties.

Ayurvedic medicine refers to a holistic healing system from India.

It is is over 3,000 years old.

What’s the Science Say about Cissus / Veld Grape?

scientific studiesThere isn’t a ton of evidence showing Cissus is effective for joint pain and stiffness, or arthritis for that matter. However there certainly is some evidence suggesting it may offer some value if you’ve recently suffered a bad bone break or fracture.

For instance…

Clinical research has shown it may have some benefit for bone healing and fracture repair. A recent scientific review of the existing scientific studies performed on this supplement concludes that Cissus does indeed benefits for bone fractures, although more high quality studies are needed.

Of course, it may offer other benefits, but the science is nowhere near as “rigorous.”

For instance…

Early animal studies suggest it may prevent the bone loss associated menopause, thus making a potentially useful supplement in the fight against osteoporosis.

In animal models, Cissus appears to help protect against ulcers caused by aspirin.

And one study showed that certain Cissus quadrangularis extracts seemed to inhibit those nasty enzymes that are associated with pain and inflammation – including COX-2 – the enzyme the prescription drug celebrex acts against.

Other studies suggest it may have a small weight loss effect as well!


knee pain

Image Courtesy Esther Max (Flickr)

Safety and Side Effects

In the course of 9 scientific studies including over 1,100 patients, no adverse reactions were reported.

This appears to be a safe supplement, especially when taken at the normal dosages.

It could lower blood sugar levels however, so exercise caution if you’re a diabetic or taking medication to lower your blood sugar. Also…

No data is available on the use of Cissus in pregnant or lactating women, so ladies… please keep that in mind!

And drug interactions?

I was unable to find any in my research on this joint supplement. Please confirm this with your own doctor before trying it for yourself.

Dosage; How much Cissus Should You Take?

I would argue that the effective dose of cissus / veld grape has yet to be established.


Most decent commercial products offer around 1,000 mg per serving, standardized for 40% “ketosterones.”

This seems like a good place to start.

If you’re only seeing a few hundred milligrams of cissus on the label of the product you’re investigating, beware…

It’s serving as “label dressing” only. In other words, it makes the ingredients profile appear more “advanced” and gives you the impression you’re getting more value for your money. It’s a scam… since the ingredient isn’t included in a dose strong enough to have any effect, it provides ZERO benefit to you.

Personal Experience

One product I’ve been using lately, Blue Star’s Joint Armour, contains 800 mg of Cissus (standardized for 5%). And while I rather like this product, there’s no way to know how much the Cissus factors into the relief it gives me because…

  1. It’s 1 of 4 total ingredients in the formula.
  2. It’s a relatively low dose of Cissus (compared to some of the other products I’ve looked at over the course of doing research for this article).

As a result, there’s no feeback I can provide that worth reading.

Customers Reviews, Feedback and Testimonials

customer reviewsFor the most part, products that contain Cissus also contain plenty of other ingredients as well, so the problem is as noted above…

… while the natural arthritis cures and remedies that boast Cissus as part of their ingredient profile may be considered helpful by consumers, the benefits those people are receiving may have nothing to do with its inclusion.


The dedicated Cissus products (meaning products that only contain Cissus and nothing else) I found are not particularly popular and have not generated enough testimonials and customer reviews to allow me to determine whether there is a concensus on whether the damn stuff is helpful or not.


For this review at least, we’re going to have leave reviews, testimonials, and personal comments completely out of the picture.


Using Cissus for any reason other than to aid the healing of broken and fractured bones seems to be pretty much a crap shoot at this point.


Cissus / veld grape definitely shows promise for stiffness and pain associated with arthritis.

Whether that promise pans out into anything more is yet to be determined!

Right now, there just isn’t enough scientific evidence to warrant a recommendation.

So I won’t provide one.

Plenty of other folks will, however.

Stay sharp. Don’t buy into the hype. If you’re seeing crazy claims of effectiveness for cissus / veld grape as an arthritis supplement, it’s not backed by science (at least, not at this time).

You’re looking at advertising spin.

Having said that…

While I wouldn’t bother with Cissus on its own, I also wouldn’t shy away from any product that contains a decent dosage of it as part of its overall formulation. I am, after all, using one myself (Blue Star’s Joint Armour), and am pretty happy with it.

Your Turn: What Do You Think?

whisperingIt is at this time that I step down from my soap box, and let you step up.


You get to have your say.

Your 15 minutes of fame.

Have you used Cissus / veld grape as a natural remedy for joint pain or arthritis?

How did it work? What dosage and product did you take?

Let us know in the comments.

We would absolutely love to hear your thoughts.

Hey! Can You Share?

It takes a fair bit of work to put these articles together, and I’d love to have them receive more exposure. So…

Can I ask a favor?

If you found this article helpful, would you mind clicking one of the share buttons hovering around on this page and sharing it on your favorite social media network (i.e., Facebook etc).

It would really help me out!

I really appreciate it! Thank you!

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